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Liposomal Cannabidiol (CBD) Formulation

Properties

Physical Form
  • Powder, Solid
  • Powder
  • Solid
Pharma and Nutraceuticals Functions
Phytochemical

Product families

Applications

Food & Nutrition — Nutrition & Well Being
  • Nutraceuticals & Supplements

Product Families

Pharmaceuticals & Nutraceuticals — Nutraceuticals & Supplements
  • Phytochemicals & Plant Extracts

Other characteristics

Brand
Liposomal
Functions
Phytochemical
Ingredient Name
CBD Distillate
Active Component
Cannabidiol (CBD)
Note

Microbiological Condition : Incubated at 30°C for 48 hours.

Odor
Slight scent of cannabis terpenes
Flavor
Mildly bittersweet flavor
Markets
Food & Nutrition
Appearance
Light yellow to off-red colored powder
Shelf LIfe
2 years
Ingredient
CBD Distillate
Technology
Pharmaceuticals & Nutraceuticals
Liposomal CBD

To make sure that CBD arrives in the gut in its active form, a solution is to incorporate it in liposomes, which are small, carefully designed phospholipid vesicles that form very stable dispersions in water. The phospholipids constitute a bilayer structure in which the CBD molecules can be safely kept dissolved, while at the same time they act as surfactants that help present them to the intestinal epithelial cells in the most optimal manner.. CBD is completely insoluble in water, poorly dissolves in alcohol and only dissolves well in oil. To be optimally absorbed in the intestines, CBD must be presented as individual molecules to the intestinal epithelial cells responsible for uptake of nutrients. In theory products with oily solutions could achieve this, but in practice the break up of an oil by the intestinal fluid and the process of dispersing it into tiny droplets ready for absorption is not straightforward and there are reports of poor bioavailability and high variability in uptake of CBD from oil products.

Labeling Claims
Non-Toxic
Product Characteristic

Appearance (upon reconstitution in deionized water) : Homogeneous, translucent dispersion free from visible particulate matter.

Instructions and Precautions

This product is of hygroscopic nature. It should be stored in a tightly closed container in a dry and dark storage place at room temperature.; Avoid long exposure to air and opening in humid environments.; Slight variations in color, taste and scent may occur among batches and are related to the source of CBD extract. These variations do not affect the product quality.

Food and Nutrition Applications
  • Dietary Supplements
  • Nutraceuticals

Technical data

Table 1 of 2

5 rows
CharacteristicValueUnit
Total Aerobic Colony Countmax. 2000cfu/g
Escherichia ColiAbsentin 10 g
EnterobacteriaceaeAbsentin 10 g
SalmonellaAbsentin 25 g
Total Yeast and Mold Countmax. 100cfu/g

Table 2 of 2

15 rows
CharacteristicValueUnitMethod
Taste and ScentMildly bittersweet flavor with a slight scent of cannabis terpenes—Organoleptic
pH (Reconstitution in Deionized Water)4.0 - 6.5—pH meter
Cannabidiol (CBD)16 - 26mg/gHPLC
THC (Total)max. 0.03% (w/w)Based on CBD content and raw material specifications
Fat Free Lecithin95 - 192mg/gHPLC
Tocopherol (and Derivatives)min. 5mg/gHPLC
Ascorbyl Palmitatemax. 30mg/gHPLC
Polysorbate 80max. 85mg/gHPLC
Histidine5 - 9mg/gHPLC
Trehalose160 - 240mg/gNA
Inulin400 - 620mg/gNA
Liposome Diameter (upon Reconstitution in Deionized Water)150 - 600nmDLS

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