Contipro Crosslinked HA
CrossLinked HA is hydrogel forming crosslinked hyaluronic acid powder. Working as a delivery system and enabling gradual release of active ingredients into the skin. The final product is a water-soluble powder with no preservatives nor stabilizers needed and has better solubility in comparison to other gelled crosslinked HA. It has more stable than HA, immediate reduction of wrinkles, higher hydrating capabilities than HMW HA, reservoir of water and active ingredients enabling their gradual release, prepared by crosslinking of an HA-derivative in the presence of standard HA.
Properties
- Physical Form
- Powder
Identification
Product families
Applications
- Skin Care
Product Families
- Skin Actives
Other characteristics
- Functions
- Anti-Aging Agent, Anti-Wrinkle Agent
- Benefit Claims
Anti-Aging, Anti-Wrinkle, Enhanced Water Binding, Hydrating, Improved Texture, Improves Skin Elasticity, Wrinkle Refinement; Anti-Aging; Anti-Wrinkle; Enhanced Water Binding; Hydrating; Improved Texture; Improves Skin Elasticity; Wrinkle Refinement
- Certifications & Compliance
- IECIC (China)
- Source
CrossLinkedHA is produced by oxidation of hyaluronic acid (300 kDa) obtained by fermentation and subsequent crosslinking of oxidized HA. Crosslinking occurs in the presence of hyaluronic acid (300 kDa) necessary for the solubility of the final powder in water.
- Markets
- Personal Care
- Shelf LIfe
- 24 months
- Solubility
Fully soluble in water, soluble in aqueous mixture of ethyl alcohol and isopropyl alcohol.
- Soluble In
Water, Aqueous mixture of ethyl alcohol and isopropyl alcohol
- Technology
- Cosmetic Ingredients
- Application Format
- Creams
- Lotions
- Masks
- Serum
- Mechanism of Action
Forms hydrogel microparticles in water. Reservoir of water and other actives inside its pores for their con - trolled release into the skin and higher efficacy. More stable than standard HA with prolonged effect.
- Certifications and Compliance
- IECIC (China)
- Examples of Safe Conditions
- pH 7
- 2 h at 70 °C or 24 h at 50°C
- pH 5
- 2 h at 50 °C or 24 h at 40°C
- pH 9
- 2 h at 50 °C or 24 h at 40°C
- Incompatible with strong oxidation or reduction agents and polymeric cationic substances, e.g. surfactants or polymers (polyquarternium-4, polyquarternium-10, etc.). Addition of multivalent metals (e.g. Zn2+, Mg2+) can modify quality of the crosslinked network.
- Compatibility and Processing
Sensitive to heat.; Extreme pH (less than 4 or more than 10) leads to decomposition of polymer, this process is accelerated by heating.
- Cosmetic Ingredients Functions
- Anti-Aging Agent
- Anti-Wrinkle Agent
- Additional Advantages
Higher resistance against hyaluronidases (enzymes present in the skin which degrade hyaluronic acid); Forms a soft hydrogel microparticle suspension in water; Decreases the irritation risk caused by some active ingredients; High water-binding capacity; Skin elasticity and texture improvement
- Recommended Concentration in Final Product
- 0.01 - 1% of solution.
