Micronised Purified Flavonoid Fraction
- Chemical Family
- Flavonoids
HTBA Micronised Purified Flavonoid Fraction is a flavonoid used as a venotonic for the chronic treatment of various cardiovascular conditions, such as CVD, varicose veins, hemorrhoids, spider veins, and heavy leg syndrome. It is a GMP-certified API that promotes blood circulation and addresses vascular discomfort. It is produced using a solvent-free method and complies with GMP standards.
Properties
- Physical Form
- Powder
Product families
Applications
- Other Pharmaceutical Manufacturing Applications
Product Families
- Active Pharmaceutical Ingredients (APIs)
Other characteristics
- Brand
- HTBA
- Labeling Claims
- Halal, Kosher, Solvent-free
- Halal
- Kosher
- Solvent-free
- Certifications & Compliance
DMF Type II, ECOVADIS, FAMI-QS, FSSC 22000, GMP, Halal, Hazard Analysis Critical Control Point (HACCP), ISO 14000, ISO 14001, ISO 9001, Kosher, SMETA-4, United States Pharmacopeia (USP), cGMP
- Grade
- Pharma Grade
- Markets
- Healthcare & Pharma
- Appearance
- Yellow to grey yellow inodorous powder
- Soluble In
- 1M sodium hydroxide, Dimethyl sulphoxide
- Insoluble In
- Water, Methanol
- Technology
- Pharmaceuticals & Nutraceuticals
- Identification
A. Infrared absorption spectrophotometry. Comparison: Micronised Purified Flavonoid Fraction working standard. B. Examine the chromatograms obtained in the assay. Results: Main peaks in the chromatogram obtained with the test solution are similar in retention time and size to the mains in the chromatogram obtained with the Micronised Purified Flavonoid Fraction working standard solution.
- Certifications and Compliance
- DMF Type II
- ECOVADIS
- FAMI-QS
- FSSC 22000
- GMP
- Halal
- Hazard Analysis Critical Control Point (HACCP)
- ISO 14000
Technical data
Table 1 of 5
3 rows| Characteristic | Value | Unit | Method |
|---|---|---|---|
| Iodine | max. 0.1 | % | — |
| Water | max. 6.0 | % | Karl Fischer |
| Sulphated ash | max. 0.2 | % | — |
Table 2 of 5
6 rows| Characteristic | Value | Unit |
|---|---|---|
| Total Aerobic Microbial Count | max. 10³ | cfu/g |
| Total Yeast and Molds Count | max. 10² | cfu/g |
| Enterobacteriae | max. 10² | PNB/g |
| Salmonella | Absence | /g |
| Escherichia coli | Absence | /g |
| Staphylococcus aureus | Absence | /g |
Table 3 of 5
1 row| Characteristic | Value | Unit |
|---|---|---|
| Particles (smaller or equal than 10 μm) | min. 90 | % |
Table 4 of 5
2 rows| Characteristic | Value | Unit |
|---|---|---|
| Any Impurity | max. 0.4 | % |
| Total Impurities | max. 1.3 | % |
Table 5 of 5
7 rows| Characteristic | Value | Unit |
|---|---|---|
| Diosmin | 87.0 - 93.0 | % |
| Hesperidin | 2.5 - 5.0 | % |
| Isorhoifolin | 0.9 - 2.8 | % |
| Linarin | 0.9 - 2.8 | % |
| Diosmetin | max. 2.0 | % |
| Total (other than diosmin) | max. 13 | % |
| Total Flavonoids | 95.0 - 102.0 | % |
