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Flavonoid Micronized Diosmin

CAS Number
520-27-4
Chemical Name
Diosmin
Molecular Formula
C₂₈H₃₂O₁₅

Bordas Micronized Diosmin, is a flavonoid harnessed as a venotonic for the enduring management of Chronic Venous Diseases (CVD), varicose veins, hemorrhoids, spider veins, and the discomfort associated with heavy leg syndrome.This GMP-certified Active Pharmaceutical Ingredient (API) is the number one in its class for the management of these pathologies. Micronisation improves bioavailability among other properties of the active ingredient

Properties

Physical Form
Powder

Product families

Pharmaceuticals & Nutraceuticals — Nutraceuticals & Supplements
  • Phytochemicals & Plant Extracts
  • Supplements & Functional Ingredients
Pharmaceuticals & Nutraceuticals — Pharmaceutical Actives & Precursors
  • Active Pharmaceutical Ingredients (APIs)

Other characteristics

Brand
Flavonoid
Synonyms

3',5,7-trihydroxy-4'-methoxyflavone-7-rutinoside, Diosmetin 7-Neohesperidoside, Diosmetin 7-O-Rutinoside, Diosmine, Neodiosmin

Active Component
Diosmin
Odor
Odorless
Appearance

Greyish-yellow or light yellow hygroscopic powder

Shelf LIfe
5 years
Soluble In

Dimethyl Sulphoxide, Dilute Solutions of Alkali Hydroxides

Insoluble In
Water, ethanol (96%)
Technology
Pharmaceuticals & Nutraceuticals
Packaging Type
  • Bags
  • Drums
Labeling Claims
  • Aflatoxin-free
  • Allergen-free
  • Animal Products-free
  • BSE-free
  • Gluten-free
  • Halal
  • Irradiation-free
  • Kosher
Packaging Information

Hermetically sealed, lined drums of 50 and 25 Kg or big-bags of 350 Kg net weight

Benefit Claims (Health)
Venotonic
Certifications and Compliance
  • Certificates of Suitability (CEP)
  • European Pharmacopeia (Ph. Eur.)
  • GMP
  • ICH Normatives
  • ISO 14000
  • ISO 45001
  • ISO 9001
  • Manufacturing License by MOH
Handling Conditions

In full and well closed container. Keep at room temperature in a dark and dry place.; Shelf Life : 5 years

Technical data

Table 1 of 3

19 rows
CharacteristicValueUnitMethod
Molecular Weight608.5——
Water Contentmax 6.0%—
Sulphated Ashmax. 0.2%—
Bulk Densitymax. 0.5g/ml—
Decomposition Point272 - 283ºC—
Pyridine Contentmax. 200ppm—
Acetic Acid Contentmax. 5000ppm—
Iodine Contentmax. 0.1%—
Particle Size (< 5μm)90.0%—
Purity (Diosmin)min. 90.0 - 102.0%HPLC
Purity (Hesperidin )max. 4.0%HPLC
Purity (Isorhoifolin)max. 3.0%HPLC

Table 2 of 3

3 rows
CharacteristicValueUnit
Escherichia coliAbsent/g
Total Aerobic Microbial Countmax. 10³CFU/g
Total Yeast and Mold Countmax. 10²CFU/g

Table 3 of 3

1 row
CharacteristicValueUnit
Heavy Metalsmax. 20ppm

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