Reproage™ peptide solution
Reproage™ peptide solution is a peptide that supports the recovery of the epidermal basal layer's stemness potential, helping to maintain its self-renewal ability and improve the appearance of mature skin. It contributes to a smoother, more radiant complexion, visually rejuvenating the skin. It has a natural origin content of 99.49%, according to ISO 16128.
Properties
- Physical Form
- Liquid
- Solution
Identification
Product families
Applications
- Skin Care
Product Families
- Skin Actives
Other characteristics
- Brand
- Reproage™
- Functions
- Anti-Aging Agent
- Benefit Claims
Anti-Aging, Complexion, Glowing Effect, Improves Skin Appearance, Promotes Youthful Skin, Regenerating, Rejuvenating, Shine & Radiance, Smoothing, Stimulating; Anti-Aging; Complexion; Glowing Effect; Improves Skin Appearance; Promotes Youthful Skin; Regenerating; Rejuvenating; Shine & Radiance; Smoothing; Stimulating
- Labeling Claims
Clean at Sephora, Credo Clean Standard, Natural, Naturally Derived, Ulta Beauty's Conscious Beauty; Clean at Sephora; Credo Clean Standard; Natural; Naturally Derived; Ulta Beauty's Conscious Beauty
- Ingredient Origin
- Natural Origin
- Certifications & Compliance
- CFDA Compliant (China), ISO 16128
- Carrier
- Aqua
- Markets
- Personal Care
- Use Levels
- 2%
- Appearance
Translucent solution containing 0.05% Acetyl hexapeptide-8.
- Soluble In
- Water
- Technology
- Cosmetic Ingredients
- Application Format
- Creams
- Leave On
- HIGHLIGHTS
Epigenetic mechanisms control gene activity beyond the information in the DNA sequence and are involved in the regulation of epidermal development. Basal cells of the epidermis (stem and progenitor cells) have the ability to proliferate giving rise to cells that then follow a process of differentiation into mature keratinocytes. In basal cells, the capacity to replenish the tissue is maintained mainly by the transcription factors OCT4, SOX2 and KLF4, markers of stem cells. Activity of these genes is regulated at the epigenetic level by microRNAs. Concretely, miR-145 represses these stem cell transcription factors, causing basal cells to stop dividing and start the process of differentiation. This involves also changes in the levels of characteristic markers, switching from the expression of keratin K14 in basal cells with stemness properties to the production of keratin K10 in suprabasal cells that are in the maturation process.. Reproage™ peptide reduces the levels of the epigenetic regulator miR-145 in skin cells and increases the typical factors of basal cells, suggesting a reactivation of the pool of epidermal progenitors. This could counteract the slowdown in regeneration occurring with age and improve skin properties, with a smoother, more radiant and visually rejuvenated appearance.
- Benefits and Features
Epigenetics brought to cosmetics; Recovery of the stemness potential; Improved complexion of both younger and older skin; Reprogramming the skin for a youthful appearance
- Skin Care Applications
- Hand Cream
- Certifications and Compliance
- CFDA Compliant (China)
- ISO 16128
- Cosmetic Ingredients Functions
- Anti-Aging Agent
