METOLOSE® SB-4
METOLOSE® consists of methyl cellulose (USP, JP, EP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, JP, EP) . METOLOSE SB-4 is an excellent sugar coating binder for solid dosage forms.
Properties
- Pharma and Nutraceuticals Functions
- Binder
- Thickener
- Viscosity Modifier
Product families
Applications
- Excipients & Coatings
Product Families
- Binders & Disintegrants
- Formulation & Processing Aids
Other characteristics
- Brand
- METOLOSE
- Functions
- Binder, Thickener, Viscosity Modifier
- Labeling Claims
- Non-Hazardous
- Certifications & Compliance
European Pharmacopeia (Ph. Eur.), Japan Pharmacopeia (JP), United States Pharmacopeia (USP)
- Grade
- Pharma Grade
- Markets
- Healthcare & Pharma
- Features
Non ionic and water soluble polymer with various viscosity.; Applicable as film strips and dispersant of liquid formulation.; SM-4 is recommendable for pellet coating as it is less sticky. The thermal gelling helps to prevent agglomerations during the coating process even at the higher spray speed.
- Appearance
White or slightly off - white powder, fibrous powder or granules.
- Technology
- Pharmaceuticals & Nutraceuticals
- Storage Information
Keep dry. Store away from excess heat and sunlight.; Store in sealed containers.
- Packaging Information
Packaging material: Double-layered polyethylene bag in fiber drum.
- Regulatory Information
This material is not hazardous as defined by 49CFR 172.101 by the U.S. department of transportation.; This substance is not classified as hazardous according to Regulation (EC) No 1272/2008 (CLP).; This substance is listed in current US Pharmacopeia, European Pharmacopeia and Japanese Pharmacopeia.
- Certifications and Compliance
- European Pharmacopeia (Ph. Eur.)
- Japan Pharmacopeia (JP)
- United States Pharmacopeia (USP)
Technical data
Table 1 of 3
9 rows| Characteristic | Value | Unit |
|---|---|---|
| Hydroxypropoxy Content | 4.0 - 7.5 | % |
| Methoxy Content | 27.0 - 30.0 | % |
| True Density | 1.26 - 1.31 | g/ml |
| Bulk Density | 0.20 - 0.45 | g/ml |
| Tapped Density | 0.35 - 0.65 | g/ml |
| Degradation Temperature | 280 - 300 | °C |
| Hygroscopicity | Depends on substitution type | — |
| Dust Explosion | 100 | bar.m/s |
| Viscosity (2 w/w % aqueous solution at 20°C) | 3.2 - 4.8 | mPa.s |
Table 2 of 3
1 row| Characteristic | Value | Unit |
|---|---|---|
| Self Ignition Temperature | approx. 360 | °C |
Table 3 of 3
1 row| Characteristic | Value | Unit |
|---|---|---|
| Angle of Repose | 35 - 50 | ° |
