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DNF-10®

DNF-10® is a protein hydrolysate from Saccharomyces cerevisiae. Active on the mediators of satiety, DNF-10® helps to lower calorie intake and reduce body fat mass. Benefits have been clinically demonstrated after the first weeks of use.

Properties

Pharma and Nutraceuticals Functions
Protein Source

Product families

Applications

Healthcare & Pharma — Drug Delivery & Care Solutions
  • Oral
Food & Nutrition — Nutrition & Well Being
  • Nutraceuticals & Supplements

Product Families

Pharmaceuticals & Nutraceuticals — Nutraceuticals & Supplements
  • Proteins & Amino Acids
Food Ingredients — Nutrition & Fortification
  • Proteins & Amino Acids

Other characteristics

Brand
DNF-10
Markets
  • Food & Nutrition
  • Healthcare & Pharma
Use Levels
500
Composition

The patented ingredient DNF-10® is an active fraction obtained after protein hydrolysis of Saccharomyces cerevisiae, a yeast species used for thousands of years in baking, fermented food and beverage manufacturing processes. The manufacturing of DNF-10® involves enzymatic proteolysis and a selection of peptides with a molecular weight <10kDa after an ultrafiltration step. The material is then spray-dried to obtain a dried powder.

Dosage Form
Powder & Powder Blends
Protein Type
Protein Hydrolysate
Technology
  • Food Ingredients
  • Pharmaceuticals & Nutraceuticals
Clinical Studies

DNF-10® benefits have been studied in several clinical studies on a total of 135 subjects involving different delivery systems.

HIGHLIGHTS

Selected peptidic fraction from Saccharomyces cerevisiae; Clinically proven benefits on a total of 135 subjects; Reduction of caloric intake significant after the first weeks (down to -600kcal/day after 8 weeks); Significant weight loss after the first month; Weight loss is from fat mass reduction; Abdominal fat and waist circumference significantly decrease; Water-soluble and heat-resistant; suitable for supplements and functional foods

Mechanism of Action

A significant action on the modulators of short-term food intake at the hypothalamic level (NPY) and at the digestive level with a reduction in the hunger hormone ghrelin have been demonstrated.. Over the longer-term, DNF-10® also regulates our cellular secretion of leptin, the satiety hormone.

Food Ingredients Functions
Protein Source

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