Niacet Sodium Acetate Pharma
Niacet’s acetates, mainly sodium acetate are used in the production of insulin. Additionally, as a constituent in insulin products, sodium acetate acts as an oxidative fuel preventing the body from producing antibodies during insulin injection. Sodium Acetate is available as an agglomerate and a powder (anhydrous) as well as a crystal (trihydrate). Sodium Acetate trihydrate is very soluble in water. Sodium Acetate anhydrous agglomerate offers the properties of non-dustiness, improved wettability, higher reactivity, higher bulk density, and improved free-flow ability.
Properties
- Physical Form
- Powder
- Solid
- Pharma and Nutraceuticals Functions
- Buffers & pH Stabilizer
Product families
Applications
- Chemical Manufacturing
- Nasal
- Ophthalmic
- Oral
- Topical
- API Manufacturing
Product Families
- Formulation & Processing Aids
- Microbial Control & Preservation
- Performance Additives
- Organic Salts
Other characteristics
- Synonyms
- NaOAc
- Functions
- Buffers & pH Stabilizer
- Dosage Form
Capsules, Creams, Foams, Gels, Lotions, Ointments, Tablets; Capsules; Creams; Foams; Gels; Lotions; Ointments; Tablets
- Labeling Claims
- Halal
- Markets
- Healthcare & Pharma
- Industrial
- Stability
Pharmaceutical grade Sodium Acetate is stable for 3 years from date of production. All other grades have 2 years stability. Physical stability and appearance may change before the end of shelf-life if not stored single-stacked in closed original packaging, dry and at room temperature
- Appearance
- White powder or agglomerate
- Shelf LIfe
- 3 years
- Technology
- Base Chemicals & Intermediates
- Pharmaceuticals & Nutraceuticals
- Plastics
- Quality Standards
- EDQM
- Background
Niacet's acetates, mainly sodium acetate but also ammonium acetate, potassium acetate, and zinc acetate are used in the production of insulin. Additionally, as a constituent in insulin products, sodium acetate acts as an oxidative fuel preventing the body from producing anti bodies during insulin injection.. Sodium acetate trihydrate at Tiel, NL site is certified by the Health Care Inspectorate – Pharmaceutical Affairs Medical Technology of the Dutch Ministry with Good Manufacturing Practices (GMP) certification. This certification affirms Niacet's commitment to supplying the highest quality active ingredients and excipients for the pharmaceutical industry.
- Applicable Processes
- Insulin Manufacturing
- Packaging Information
Depending on product form in 20kg or 25kg polyethylene lined paper bags, 450kg, 500kg, 900kg, 990kg and 1000kg big bags.
- Certifications and Compliance
- GMP
- REACH (Europe)
Technical data
Table 1 of 2
9 rows| Characteristic | Value | Unit |
|---|---|---|
| Heavy metals Content | max. 2 | ppm |
| Assay Content | 99-101 | — |
| Sulphate Content | max. 50 | ppm |
| Water Content | max. 0.5 | % |
| Chloride content | max. 200 | ppm |
| Insoluble In Water | max. 200 | ppm |
| pH (1% solution) | 8.0 - 9.0 | — |
| Melting Point | 324 | °C |
| Auto-ignition temperature | 607 | °C |
Table 2 of 2
1 row| Characteristic | Value | Unit |
|---|---|---|
| Solubility(ies)(25°C) | 505 | kg/m³ |
