HEPPE MEDICAL CHITOSAN GMBH Chitosan
Chitosan is a nitrogenous polysaccharide. The monomer of chitosan is glucosamine. Chitosans in dissolved form are positively charged. Due to their different degrees of deacetylation and molecular weights, chitosans are a large group of substances with different properties.
Properties
- Pharma and Nutraceuticals Functions
- Anti-Fungal Agent
- Anti-Inflammatory
- Anti-Microbial Agent
- Bacteriostatic Agent
Product families
Applications
- Other Drug & Care Solutions
- Transdermal
- Wound Care
Product Families
- Microbial Control & Preservation
- Active Pharmaceutical Ingredients (APIs)
Other characteristics
- Synonyms
- poliglusam
- Functions
Anti-Fungal Agent, Anti-Inflammatory, Anti-Microbial Agent, Bacteriostatic Agent
- Labeling Claims
- Non-Toxic
- Markets
- Healthcare & Pharma
- Appearance
White to Light Yellow (Solid), Clear, Colorless to Slightly Yellowish (Solution)
- Properties
Biodegradable by enzymes, non-toxic; Detected in the human body as an endogenous substance; Inhibiting the growth of bacteria and fungi; Film- and fiber-forming, cross-linking; Anti-inflammatory; Haemostatic, wound-healing; Odor-absorbing, capable of bonding to proteins, heavy metals, suspended solids; Having a stimulating effect on the immune system and metabolism; Not thermo-elastic, decomposes at 280° C; pKa 6.3; High charge carrier density; Biodegradable; Non-toxic; Bacteriostatic; Fungistatic; Film and fiber forming, cross-linking; Immobilization of living organisms; Anti-inflammatory, improves wound healing; Stimulation of immune system and metabolism; Deodorizing; Bonding ability to proteins, heavy metals and aerosols
- Shelf LIfe
- 36 Months
- Soluble In
- Diluted Acids (pH - max. 6)
- Derivatives
Chitin and chitosan derivatives are extremely versatile. Most of them are directly soluble in water and, depending on their derivatisation, can be applied in neutral and basic pH ranges. Thus, the derivatives have very comprehensive and customized potential applications. Our standard derivatives include:; Chitosan HCl; N, O-Carboxymethyl-Chitosan (CMC); Chitosan Lactate; Chitosan Acetate; Chitosan Glutamate
- Insoluble In
- Water, Sulphuric Acid
- Technology
- Pharmaceuticals & Nutraceuticals
- Benefit Claims
- Stimulates Immune System
- Chitosan Oligomer
Chitosan oligosaccharide is an oligomer of β-(1 ➔ 4)-linked d-glucosamine. Chitosan oligomer can be prepared from the deacetylation and hydrolysis of chitin.
- Production Process
Chitosan differs from chitin in that it has free amino groups (figure 1) and is obtained by deacetylizing chitin. At a minimum deacetylization level of 70% (=amount of free amino groups in the polymer) it is considered to be chitosan. The monomer of chitosan is D-amino glucose.
- Manufacturing Process
In the deacetylation process, chitin is subjected to treatment with concentrated lye to dissociate acetyl groups from the polymer. The result is chitosan that, depending on the degrees of deacetylation and polymerization (chain length), has more or less pronounced properties.
Technical data
Table 1 of 3
8 rows| Characteristic | Value | Unit | Method |
|---|---|---|---|
| Dry matter content | min. 85 | % | HMC QK-PA-0006 |
| Degree of Deacetylation | 80 - 95 | % | HMC QK-PA-0014 |
| Viscosity (1% in Acetic Acid, 20°C) | min. 5 | mPas | HMC QK-PA-0004 |
| pH (1% in Water, 20°C) | 3 - 7 | — | HMC QK-PA-0013 |
| Ash Content (Sulphated) | max. 1 | % | HMC QK-PA-0005 |
| Insolubles | max. 2 | % | HMC QK-PA-0010 |
| Molecular Weight | approx. 30 - 200 | kDa | — |
| Protein content | max. 0.5 | % | — |
Table 2 of 3
1 row| Characteristic | Value | Unit | Method |
|---|---|---|---|
| Total Bacterial Count | max. 1000 | cfu/g | HMC QK-PA-0022 |
Table 3 of 3
4 rows| Characteristic | Value | Unit | Method |
|---|---|---|---|
| Mercury Content | max. 0.2 | ppm | HMC QK-PA-0020 |
| Cadmium Content | max. 0.5 | ppm | HMC QK-PA-0020 |
| Lead Content | max. 40 | ppm | HMC QK-PA-0019 |
| Arsenic Content | max. 0.5 | ppm | HMC QK-PA-0020 |
