PolyKoVidone® XL-10
NKY Pharma PolyKoVidone XL-10 are an essential ingredient to formulating highly effective pharmaceutical products. The polymers are produced in a state of the art manufacturing facility operating under full cGMP compliance. In addition, all physical handling and packaging of powders is conducted in class-D clean rooms with specific attention placed on reducing the risk of any potential particulate/foreign matter contamination. PolyKoVidone® possesses dual binding and disintegration properties while enhancing active solubilization. The product is used in the Pharma applications.
Properties
- Physical Form
- Powder
- Solid
- Pharma and Nutraceuticals Functions
- Complexing Agent
- Disintegrant
- Solubilizer
- Stabilizer
- Suspending Agent
Product families
Applications
- Oral
- Transdermal
Product Families
- Binders & Disintegrants
- Emulsifiers & Stabilizers
- Formulation & Processing Aids
- Solvents & Solubilizers
Other characteristics
- Brand
- PolyKoVidone
- Synonyms
1-Vinyl-2-pyrrolidinone polymer, 1-Vinyl-2-pyrrolidone homopolymer, 1-Vinyl-2-pyrrolidone polymer, 1-Vinylpyrrolidin-2-one homopolymer, n-Octyl mercaptan-N-vinylpyrrolidone copolymer, N-Vinyl-2-pyrolidone homopolymer, N-Vinyl-2-pyrrolidinone homopolymer, N-Vinyl-2-pyrrolidone homopolymer, N-Vinyl-2-pyrrolidone polymer, N-Vinylbutyrolactam polymer, N-Vinylpyrrolidinone homopolymer, N-Vinylpyrrolidinone polymer, N-Vinylpyrrolidone homopolymer, N-Vinylpyrrolidone polymer, Poly(1-vinyl-2-pyrrolidinone), Poly(1-vinyl-2-pyrrolidone), Poly(1-vinylpyrrolidinone), Poly(N-vinyl-2-pyrrolidinone), Poly(N-vinyl-2-pyrrolidone), Poly(N-vinyl-γ-butyrolactam), Poly(N-vinylbutyrolactam), Poly(N-vinylpyrrolidinone), Poly(N-vinylpyrrolidone), Poly(vinylpyrrolidinone), Poly(vinylpyrrolidone), Polyvinyl polypyrrolidone, Polyvinylpyrrolidone, Povidone, Vinylpyrrolidinone polymer, Vinylpyrrolidone homopolymer, Vinylpyrrolidone polymer
- Functions
Complexing Agent, Disintegrant, Solubilizer, Stabilizer, Suspending Agent
- Dosage Form
Capsules, Dispersions, Granules, Suspension, Tablets; Capsules; Dispersions; Granules; Suspension; Tablets
- Certifications & Compliance
British Pharmacopeia (BP), European Pharmacopeia (Ph. Eur.), Indian Pharmacopeia, Japan Pharmacopeia (JP), Korean Pharmacopeia, United States Pharmacopeia (USP), cGMP
- Grade
- Pharma Grade
- Markets
- Healthcare & Pharma
- Technology
- Pharmaceuticals & Nutraceuticals
- HIGHLIGHTS
Hygroscopic.; Insoluble in water, acid, alkaline and all other common solvents.; Swells rapidly in water without gel formation.; Improves flowability and plasticity.; Strong particle compressibility.; Non-ionic; Chemically inert; Low Peroxide content.
- Manufacturing Technology
- Direct Compression
- Dry Granulation
- Wet Granulation
- Certifications and Compliance
- British Pharmacopeia (BP)
- European Pharmacopeia (Ph. Eur.)
- Indian Pharmacopeia
- Japan Pharmacopeia (JP)
- Korean Pharmacopeia
- United States Pharmacopeia (USP)
- cGMP
- Known For
Super disintegrant; due to its excellent swelling characteristics in water, PolyKoVidone® can be used as water insoluble disintegrant for wet and dry granulation processes. The material can be added either before or after granulation in direct compression tableting processes. It exhibits high capillary activity and pronounced hydration capacity, without the formation of gel.; Solubility enhancer; PolyKovidone® increasing the solubility of poorly soluble drugs via co-evaporation processes.; Suspension stabilizer; PolyKoVidone® increasing the viscosity and improves the dispersion properties to reduce the sedimentation rate of drugs, meanwhile increasing the re-dispersibility of said sediment. Suitable for liquid and instant oral preparations.; Complexing agent of drug ingredients; PolyKoVidone® stabilizes active ingredients in pharmaceutical products, improving drug solubility and bioavailability.
