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OraRez® W MA – Diacid

CAS Number
25153-40-6
EC Number
607-572-6
Chemical Name
Poly(Methylvinyl Ether-Co-Maleic Acid)

OraRez® W MA – Diacid is an outstanding mucoadhesiving showing the ability to complex, solubilize and retain actives on the mucosal tissue. The material’s bioadhesive properties’ and unique structure makes it an invaluable component to pharmaceutical products.

Properties

Pharma and Nutraceuticals Functions
  • Chelating Agent
  • Controlled Release Agent
  • Film Former
  • Mucoadhesive
  • Solubilizer

Product families

Applications

Healthcare & Pharma — Drug Delivery & Care Solutions
  • Transdermal

Product Families

Pharmaceuticals & Nutraceuticals — Excipients
  • Formulation & Processing Aids
  • Modified & Controlled Release
  • Other Excipients
  • Pharmaceutical Coatings
  • Solvents & Solubilizers

Other characteristics

Brand
OraRez
Synonyms

Maleic acid-methoxyethylene copolymer, Maleic acid-methyl vinyl ether copolymer, Maleic acid-methyl vinyl ether polymer, Maleic acid-vinyl methyl ether copolymer, Methoxyethylene-maleic acid copolymer, Methyl vinyl ether-maleic acid copolymer, Methyl vinyl ether-maleic acid polymer, Poly(maleic acid-methyl vinyl ether), Poly(methyl vinyl ether-maleic acid), Vinyl methyl ether-maleic acid copolymer

Functions

Chelating Agent, Controlled Release Agent, Film Former, Mucoadhesive, Solubilizer

Dosage Form
Transdermal Patches
Markets
Healthcare & Pharma
Soluble In
Water
Technology
Pharmaceuticals & Nutraceuticals
HIGHLIGHTS

Biocompatible water-soluble film former.; Excellent bioadhesive/mucoadhesive properties.; Excellent chelating properties.; Enhances solubilization and retention of actives and drugs.; Broad molecular weight range and tunable rheology.; Polyanion having two distinct pKa's.

Known For

Retention of drugs on mucosal tissue.; Water-soluble, pain-free adhesive applications (e.g. ostomy bags, buccal patchs).; Solubilization/retention of actives in the oral cavity.; PVM/MA-polymer or PVM/MA-drug complex systems for controlled release.; Enteric coatings and systems.; Hydrogel dressing.

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