Aether Industries Limited Meglumine (N-Methyl-D-Glucamine)
- CAS Number
- 6284-40-8
- EC Number
- 228-506-9
- Chemical Name
- N-Methyl-D-Glucamine
- Chemical Family
- Carbohydrates, GlucosaminesCarbohydratesGlucosamines
N-Methyl-D-Glucamine (NMDG) is an advanced intermediate part of Aether's pharmaceutical portfolio. It is useful in the pharma, dyes and pigments industries applications. Most common end API forms include Meglumine (a sugar alcohol excipient), Gadopentetate (a contrast agent used in MRI and Xray dyes) and Fosaprepitant (used in antiemetic medications to prevent nausea and vomiting in cancer patients undergoing chemotherapy treatments).
Properties
- Physical Form
- Crystals
- Powder
- Solid
- Pharma and Nutraceuticals Functions
- API Intermediate
Identification
- Molecular Formula
- C₇H₁₇NO₅
Product families
Applications
- Chemical Manufacturing
- API Manufacturing
Product Families
- Other Intermediates
- Intermediates & Precursors
Other characteristics
- Synonyms
- 1-Deoxy-1-methylaminosorbitol, Meglumine
- Functions
- API Intermediate, Intermediate
- Markets
- Healthcare & Pharma
- Industrial
- Storage
- Dry and well ventilated place
- Appearance
- White to off white crystalline powder
- Shelf LIfe
- 3 Years
- Technology
- Base Chemicals & Intermediates
- Pharmaceuticals & Nutraceuticals
- Packaging Type
- Bags
- Specifications
Test and Specification are changed to meets the requirement as per USP39.
- Quality Standards
- ENISO 9001:2015
- GMP
- End API Application
- Meglumine, Gadopentetate and Fosaprepitant.
- Applicable Processes
- Dye Manufacturing
- Pharmaceutical Manufacturing
- Pigment Manufacturing
- Handling Precautions
Wear personal protective equipment and ensure adequate ventilation.
- Acceptable Containers
Tightly closed LDPE sample bag with secondary bag.
- Base Chemicals End Uses
- Fosaprepitant
- Gadopentetate
- Meglumine
- Product Characteristic
Identification - The mixture turns bright yellow and becomes clear.; Reducing substance - The color of solution does not change.
- Base Chemicals Functions
- Intermediate
- Certifications and Compliance
- GMP
- ISO 14001
- ISO 45001
Technical data
Table 1 of 2
1 row| Characteristic | Value | Unit |
|---|---|---|
| Molecular Weight | 195.21 | g/mol |
Table 2 of 2
10 rows| Characteristic | Value | Unit |
|---|---|---|
| Melting Point | 128 - 132 | °C |
| Identification | The mixture turns bright yellow and becomes clear | — |
| Clarity of Solution | Clear solution | — |
| Loss on Drying | max. 1.0 | % w/w |
| Residue on Ignition | max. 0.1 | % w/w |
| Heavy Metal | max. 0.002 | % |
| Specific Rotation | -15.7 to -17.3 | ° |
| Absorbance | max. 0.0300 | — |
| Residual Solvent (Methanol) | max. 3000 | ppm |
| Assay by Titration | 99.0 - 100.5 | % w/w |
