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Bachem EXENATIDE ACETATE

CAS Number
141758-74-9
EC Number
686-356-3
Molecular Formula
C184H282N50O60S

Bachem EXENATIDE ACETATE is a 39-amino acid peptide originally isolated from the salivary glands of the Gila monster (Heloderma suspectum), differs from exendin-3 only in two positions close to the N-terminus. Application of exenatide causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide augments the postprandial production of insulin and suppresses secretion of glucagon.

Identification

Chemical Name

Exendin 3 (Heloderma horridum), 2-glycine-3-L-glutamic acid-; Exendin 3 (Heloderma horridum) 2-glycine-3-L-glutamic acid-

Product families

Applications

Healthcare & Pharma — Pharmaceutical Manufacturing
  • Other Pharmaceutical Manufacturing Applications

Product Families

Pharmaceuticals & Nutraceuticals — Pharmaceutical Actives & Precursors
  • Active Pharmaceutical Ingredients (APIs)

Other characteristics

Certifications & Compliance
DMF Type I, cGMP
Markets
Healthcare & Pharma
Sequence

H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 acetate salt.

Technology
Pharmaceuticals & Nutraceuticals
Long-term Storage
-20 ± 5 °C
Fields of Application
Diabetes II
Certifications and Compliance
  • DMF Type I
  • cGMP
Regulatory Documentation
DMF

Technical data

Table 1 of 1

1 row
CharacteristicValueUnit
Relative Molecular Mass4186.63g/mol

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